Veterinary Drugs & Dosages Table
Hare and Rabbit

THIS SECTION IS INTENDED AS A REFERENCE FOR VETERINARY SURGEONS ONLY

Any medications dispensed or administered, or procedures performed, should only be by or under order of a qualified, licensed veterinary surgeon.
Given the current scarcity of drugs licensed for use in wildlife, the responsible use of the cascade system is recommended.
Drug information and dosages are derived from a variety of sources (see references), and do not necessarily guarantee safety or efficacy
.

 

ANTIBIOTICS    ANALGESICS & ANTI-INFLAMMATORIES    ANAESTHETICS & SEDATIVES    ANTHELMENTICS    FLUIDS    OTHER
MYXOMATOSIS TREATMENT


ANTIBIOTICS

• Lincomycin TOXIC in rabbits
• Antibiotic associated diarrhoea from clindamycin, oral ampicillin
• Penicillin should be reserved for treating treponematosis
• Giving antibiotics parenterally less likely to cause diarrhoea than if given orally
• Antibiotics need concurrent pro-biotic supplement to reinstate gut flora

DRUG

DOSE

ROUTE

DIRECTIONS

USES/NOTES

Amoxicillin and clavulanic acid
(Synulox/Augmentin)

NO

 

 

In common with all other penicillins, Synulox should not be administered to rabbits

Cefalexin

15mg/kg

SC

BID

Antibiotic

 

20mg/kg

SC

SID

Antibiotic

Chlortetracycline hydrochloride, benzocaine (Aureomycin)

50mg/kg

PO

SID

 

Enrofloxacin (Baytril 5%)

5mg/kg

SC

BID

Licensed for use in rabbits

 

10mg/kg

SC

SID

 

 

5-10mg/kg

PO

BID

 

Fusidic acid eye drops

1 drop/eye

topical

SID

Conjunctivitis

Gentamicin (Tiacil, Virbac)

1-2 drops/eye

topical

TID

Conjunctivitis

Metronidazole (Flagyl)

20mg/kg

PO

BID

Antibacterial treatment of enterotoxaemia

Oxytetracycline

15mg/kg

SC, IM

SID

 

 

1mg/ml

PO

Drinking water

 

 

50mg/kg

PO

 

 

Penicillin

40mg/kg

SC

Daily for 5 days

Treponematosis

Sulphadimidine

0.2% solution

PO

Diluted with water

Coccidia

Trimethoprim/sulfadiazine

30mg/kg

PO

 

 

 

48mg/kg

SC

 

 

Trimethoprimsulfamethoxazole

40mg/kg

PO

BID

Coccidiosis

 


ANALGESICS & ANTI-INFLAMMATORIES
  • For pain and inflammation use NSAID’s

DRUG

DOSE

ROUTE

DIRECTIONS

USES/NOTES

Buprenorphine (Temgesic/Vetergesic)

0.01-0.05mg/kg

IV, SC

6-12hrs duration

Analgesic

Butorphanol

0.1-0.5mg/kg

SC, IM, IV

2-4hrs duration

Analgesic

Carprofen (Rimadyl/Zenecarp)

2-4mg/kg

SC

SID

Analgesic

Ketoprofen

3mg/kg

PO

BID

Analgesic. Care in hypotensive patients

Meloxicam

0.1-0.2mg/kg

PO

SID

Palatable

Pethidine

5-10mg/kg

SC, IM

2-3 hrs duration

 

 


ANAESTHETICS & SEDATIVES

DRUG

DOSE

ROUTE

DIRECTIONS

USES/NOTES

Acepromazine

0.1 – 0.5mg/kg

IM, SC

 

Sedation NOT analgesic

Acepromazine+ butorphanol

0.5mg/kg + 0.5mg/kg

IM, SC

 

Sedation. Can be mixed in syringe. Vasodilator

Adrenaline

20mcg/kg

SC, IV

 

Cardiac arrest. Can be given into the trachea

Atipamezole (Antisedan)

1mg/kg

SC, IM, IV

 

Reversal of medetomidine

Atropine

0.05mg/kg (50mcg/kg)

IM

 

Pre-med. Atropinesterase, which metabolizes atropine, is produced by 40% of rabbits so glycopyrrolate is preferable

Diazepam (Valium)

1-2mg/kg

IV, IM

 

Sedation

Fentanyl/fluanisone

0.2-0.3ml/kg

IM, SC

 

Pre-med, GA, analgesic

Glycopyrrolate

0.01mg/kg

IV

 

Pre-med. Does not cross blood-brain barrier and cause myiasis

 

0.2mg/kg

SC, IM

 

Organophosphate poisoning

Ketamine

25-50mg/kg

IM

 

Sedation. Can be used in combination

Ketamine + xylazine

35mg/kg + 5mg/kg

IM

 

Anaesthesia

Ketamine + medetomidine

10mg/kg + 0.2mg/kg

IM

 

Anaesthesia

Ketamine + medetomidine + Butorphanol

10mg/kg + 0.2mg/kg + 0.5mg/kg

IM

 

Anaesthesia with pre-emptive analgesia

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ANTHELMENTICS
  • Do not use Fipronil

DRUG

DOSE

ROUTE

DIRECTIONS

USES/NOTES

Fenbendazole

20mg/kg

PO

 

 

Griseofulvin

25mg/kg

PO

SID for 2 weeks

Ringworm

Imidacloprid (Advantage)

10mg/kg

topical

2-3 areas on dorsum

Fleas

Ivermectin

400mcg/kg

 

Repeat after 10-14 days

Endoparasites, esp ear mites

Praziquantel (Droncit)

6mg/kg

 

Repeat after 10 days

Cestodes

Selamectin

12mg/kg

topically

 

 

 


FLUIDS

DRUG

DOSE

ROUTE

DIRECTIONS

USES/NOTES

Isotonic fluids
e.g. Hartmann’s

Between 70-150ml/kg/day

Mainly SC route

Warm fluids. No more than 50ml/kg bolus at one time/site

Assume minimum 10% dehydration on arrival, add as appropriate

Hartmann’s

120ml/kg/day

SC

Split into 3 treatments

maintenance

Crystalloids e.g. Ringer’s

10 to 15ml/kg

IV

over 5 to 10 minutes

hypovolemic shock

Hetastarch

5ml/kg

IV

over 5 to 10 minutes

hypovolemic shock

 

OTHER  *1

DRUG

DOSE

ROUTE

DIRECTIONS

USES/NOTES

Cimetidine (Tagamet) *3

5-10mg/kg

PO

Every 6-12hrs

Gastric and duodenal ulcers

Cisapride (Propulsid)

0.5mg/kg

PO

Every 8-12hrs

Enhances gastrointestinal motility – used for GI stasis

Dexamethasone

1-3mg/kg

IM, IV

 

Anti-inflammatory

Doxapram (Dopram)

5mg/kg

IM, IV

 

Respiratory stimulant

Frusimide (lasix 5%) *4

2-5mg/kg

PO, SC, IM, IV

Every 12hrs

Diuretic

Metoclopramide

0.5mg/kg

SC, PO,

BID

Motility stimulant. May not be effective in young rabbits

Pentobarbital sodium (Pentobarbital) *2

150 mg/kg

IV, IP

General anaesthesia FIRST

Euthanasia

Prednisolone

0.5-2mg/kg

PO, IM, SC

 

 

Ranitidine (Zantac) *3

2-5mg/kg

PO

BID

Gastric ulceration, often in in-appetent rabbits

Vitamin K *2

1-10mg/kg

IM

 

Select bleeding disorders and toxicities

Vitamin C *2

100mg/kg

PO

BID

Nutritional supplement

Vaccination
Viral Haemorrhagic Disease

See Data Sheet

 

Nobivac Myxo (Intervet Schering-Plough)

 

Vaccination
Myxomatosis

See Data Sheet

 

Cylap (Fort Dodge Animal Health)

 

 


MYXOMATOSIS TREATMENT
   *1

DRUG     

DOSE

FREQUENCY

EFFECT/USES

Avipro

pinch

SID on food

Pro-biotic

Bisolvon powder

One sprinkle

SID on food

Once course is finished

Bromhexine hydrochloride

0.3ml

SID for 7 days

Mucolytic

Enrofloxacin 5%

0.2ml

SID for 7 days

Antibiotics

Etamiphylline camsylate

0.2ml

SID for 7 days

 

Flunixin

0.15ml

SID for 3 days

Anti toxin

Hartmann’s solution

50ml

BID for 7 days

Rehydration

Multivitamins

Up to 0.5ml

Once weekly

Multivitamins

 

References


BSAVA Manual of Wildlife Casualties
*1           Practical Wildlife Care, Second Edition, Les Stocker
*2           BSAVA Small Animal Formulary 6th Edition
*3           BSAVA Manual of Rabbit Medicine and Surgery Second Edition
*4           Ferrets, Rabbits and Rodents - Clinical Medicine and Surgery Second Edition
*5           Rabbit Medicine and Surgery Jerry LaBonde MS, DVM

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